Chinese Scientists Announce 'Safe' Way To Create Stem Cells

Earlier this week Chinese researchers announced that they had ?invented an "easy and safe way" to create stem cells.

Should this be true, this kind of breakthrough has the potential to enhance the development of what is often referred to as therapeutic cloning treatments. These types of treatments encourage the cloning and generation of tissues and organs for treatment of diseases.

The method, was published in the U.S. journal Science. In it, the Chinese scientists discuss how a medley of small-molecule compounds were used to reprogram somatic cells to a pluripotent state. Doing this gave these cells the ability to differentiate into any other type of cell in the body.

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The previous method of accomplishing this had been extremely complicated--and as a result of that complication, limited the clinical uses of such cells. This new method however has no such drawback. ?Professor Deng Hongkui of Peking University. the leader of the Chinese team, said in their study that his team validated "a whole new route" to pluripotent stem cells. ?

"Small molecules have advantages because they can be cell permeable, non-immunogenic, more cost-effective, and can be more easily synthesized, preserved, and standardized," the researchers wrote in their paper.

To characterize their differentiation potential, they injected the chemically induced pluripotent stem cells (CiPSCs) into immunodeficient mice. After doing so, the scientists realized that the cells had ?begun to differentiate into tissues of all three germ layer.

Unlike mice generated through previous methods, the mice generated from CiPSCs were "100 percent viable and apparently healthy for up to 6 months," the Chinese team wrote.

Using the CiPSCs technology, the researchers have successfully created several healthy laboratory mice.

With the invention of this new method of stem cell creation, the researchers believe that their findings ?open up all sorts of possibilities when it comes to curing or treating diseases with cloned or altered tissues.

"To date, the complete chemical reprogramming approach remains to be further improved to reprogram human somatic cells and ultimately meet the needs of regenerative medicine," they wrote.

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Source: http://www.designntrend.com/articles/6317/20130719/chinese-scientists-announce-safe-way-create-stem-cells.htm

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