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INDIANAPOLIS (AP) ? Seth Curry shot Duke right into the regional finals ? and put Mike Krzyzewski on the verge of another major milestone.
Curry scored 29 points to lead the second-seeded Blue Devils past third-seeded Michigan State 71-61 on Friday night and into the Midwest Regional final.
If Duke (30-5) beats top-seeded Louisville (32-5) in Sunday's regional final, Krzyzewski would tie John Wooden's record with 12 Final Four trips.
Michigan State (27-9) just couldn't keep up with Curry and Duke's shooters. The Spartans were led by Keith Appling with 16 points and Adreian Payne with 14.
Curry's sixth 3 of the game broke a 38-38 tie early in the second half, sending Duke on a 9-0 run. It never trailed again.
Source: http://news.yahoo.com/curry-sends-duke-past-michigan-st-71-61-042125230--spt.html
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Mar. 27, 2013 ? Scientists at Harvard may have new hope for anyone who's tried to fight the battle of the bulge.
New research, conducted in collaboration with researchers at Massachusetts General Hospital, has found that the gut microbes of mice undergo drastic changes following gastric bypass surgery. Transfer of these microbes into sterile mice resulted in rapid weight loss. The study is described in a March 27 paper in Science Translational Medicine.
"Simply by colonizing mice with the altered microbial community, the mice were able to maintain a lower body fat, and lose weight -- about 20% as much as they would if they underwent surgery," said Peter Turnbaugh, a Bauer Fellow at Harvard's Faculty of Arts and Sciences (FAS) Center for Systems Biology, and one of two senior authors of the paper.
But as striking as those results were, they weren't as dramatic as they might have been.
"In some ways we were biasing the results against weight loss," Turnbaugh said, explaining that the mice used in the study hadn't been given a high-fat, high-sugar diet to increase their weight beforehand. "The question is whether we might have seen a stronger effect if they were on a different diet."
"Our study suggests that the specific effects of gastric bypass on the microbiota contribute to its ability to cause weight loss and that finding ways to manipulate microbial populations to mimic those effects could become a valuable new tool to address obesity," said Lee Kaplan, director of the Obesity, Metabolism and Nutrition Institute at MGH and the other senior author of the paper.
"We need to learn a good deal more about the mechanisms by which a microbial population changed by gastric bypass exert its effects, and then we need to learn if we can produce these effects -- either the microbial changes or the associated metabolic changes -- without surgery," Kaplan, an associate professor of Medicine at Harvard Medical School, added. "The ability to achieve even some of these effects without surgery would give us an entirely new way to treat the critical problem of obesity, one that could help patients unable or unwilling to have surgery."
While the results were exciting, Turnbaugh warned that it may be years before they could be replicated in humans, and that such microbial changes shouldn't be viewed as a way to lose those stubborn last 10 pounds without going to the gym. Rather, the technique may one day offer hope to dangerously obese people who want to lose weight without going through the trauma of surgery.
"It may not be that we will have a magic pill that will work for everyone who's slightly overweight," he said. "But if we can, at a minimum, provide some alternative to gastric bypass surgery that produces similar effects, it would be a major advance."
While there had been hints that the microbes in the gut might change after bypass surgery, the speed and extent of the change came as a surprise to the research team.
In earlier experiments, researchers had shown that the guts of both lean and obese mice are populated by varying amounts of two types of bacteria, Firmicutes and Bacteroidetes. When mice undergo gastric bypass surgery, however, it "resets the whole picture," Turnbaugh said.
"The post-bypass community was dominated by Proteobacteria and Proteobacteria, and had relatively low levels of Firmicutes," he said. What's more, Turnbaugh said, those changes occurred within a week of the surgery, and weren't short-lived -- the altered gut microbial community remained stable for months afterward.
While the results may hold out the hope for weight loss without surgery, both Turnbaugh and Kaplan warned that future studies are needed to understand exactly what is behind the weight loss seen in mice.
"A major gap in our knowledge is the underlying mechanism linking microbes to weight loss," Turnbaugh said. "There were certain microbes that we found at higher abundance after surgery, so we think those are good targets for beginning to understand what's taking place."
In fact, Turnbaugh said, the answer may not be the specific types of microbes, but a by-product they excrete.
In addition to changes in the microbes found in the gut, researchers found changes in the concentration of certain short-chain fatty acids. Other studies, Turnbaugh said, have suggested that those molecules may be critical in signaling to the host to speed up metabolism, or not to store excess calories as fat.
Going forward, Turnbaugh and Kaplan hope to continue to explore those questions.
"We think such studies will allow us to understand how host/microbial interactions in general can influence the outcome of a given diet," Kaplan said. "To some degree, what we're learning is a comfort for people who have an issue with their weight, because more and more we're learning that the story is more complicated than just how much you exercise and how much you eat."
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/living_well/~3/55s2_HYwLsA/130327144124.htm
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Emir of Qatar Sheik Hamad Bin Khalifa Al Thani, center, attends the opening session of the Arab League Summit in Doha, Qatar, Tuesday, March 26, 2013. Syrian opposition representatives took the country's seat for the first time at an Arab League summit that opened in Qatar on Tuesday, a significant diplomatic boost for the forces fighting President Bashar Assad's regime. (AP Photo/Ghiath Mohamad)
Emir of Qatar Sheik Hamad Bin Khalifa Al Thani, center, attends the opening session of the Arab League Summit in Doha, Qatar, Tuesday, March 26, 2013. Syrian opposition representatives took the country's seat for the first time at an Arab League summit that opened in Qatar on Tuesday, a significant diplomatic boost for the forces fighting President Bashar Assad's regime. (AP Photo/Ghiath Mohamad)
Egyptian President Mohammed Morsi, center, attends the opening session of the Arab League summit in Doha, Qatar, Tuesday, March 26, 2013. Syrian opposition representatives took the country's seat for the first time at an Arab League summit that opened in Qatar on Tuesday, a significant diplomatic boost for the forces fighting President Bashar Assad's regime. (AP Photo/Ghiath Mohamad)
Egyptian President Mohammed Morsi, center, attends the opening session of the Arab League summit in Doha, Qatar, Tuesday, March 26, 2013. Syrian opposition representatives took the country's seat for the first time at an Arab League summit that opened in Qatar on Tuesday, a significant diplomatic boost for the forces fighting President Bashar Assad's regime. (AP Photo/Ghiath Mohamad)
Khaled Saleh, a spokesman for the Syrian National Coalition, speaks during the opening session of the Arab League Summit in Doha, Qatar, Tuesday, March 26, 2013. Syrian opposition representatives took the country's seat for the first time at an Arab League summit that opened in Qatar on Tuesday, a significant diplomatic boost for the forces fighting President Bashar Assad's regime. (AP Photo/Ghiath Mohamad)
Saudi Crown Prince Salman bin Abdul Aziz al-Saud, left, attends the opening session of the Arab League Summit in Doha, Qatar, Tuesday, March 26, 2013. Syrian opposition representatives took the country's seat for the first time at an Arab League summit that opened in Qatar on Tuesday, a significant diplomatic boost for the forces fighting President Bashar Assad's regime. (AP Photo/Ghiath Mohamad)
DOHA, Qatar (AP) ? Qatar's emir looked over an assembly of Arab leaders Tuesday as both cordial host and impatient taskmaster. His welcoming remarks to kings, sheiks and presidents across the Arab world quickly shifted to Qatar's priorities: Rallying greater support for Syrian rebels and helping Palestinians with efforts such as a newly proposed $1 billion fund to protect Jerusalem's Arab heritage.
No one seemed surprised at the paternal tone or the latest big-money initiative. In a matter of just a few years, hyper-wealthy Qatar has increasingly staked out a leadership role once held by Egypt and helped redefine how Arab states measure influence and ambition.
Little more than a spot to sink oil and gas wells a generation ago, Qatar is now a key player in nearly every Middle Eastern shakeout since the Arab Spring, using checkbook diplomacy in settings as diverse as Syria's civil war, Italian artisan workshops struggling with the euro financial crisis, and the soccer pitches in France as owners of the Paris Saint-Germain team.
As hosts of an Arab League summit this week, Qatar gets another chance to showcase its swagger.
With power, however, come tensions. Qatar has been portrayed as an arrogant wunderkind in places such as Iraq and Lebanon where some factions object to its rising stature, and Qatar's growing independent streak in policy-making has raised concerns among its Gulf Arab partners. It also faces questions ? as do other Gulf nations and Western allies ? over support for some Arab Spring uprisings while remaining loyal to the embattled monarchy in neighboring Bahrain.
"The adage that money buys influence could very well be the motto of Qatar," said Abdulkhaleq Abdulla, a professor of regional politics at Emirates University outside Abu Dhabi. "But it goes beyond that. Qatar also has learned the value of being flexible and, at the same time, thinking big."
It's hard these days to find a point on the Mideast map without some link back to Qatar.
In recent years, Qatar mediated disputes among Lebanese factions and prodded Sudan's government into peace talks with rebels in the Darfur region. Qatar's rulers even broke ranks with Gulf partners and allowed an Israeli trade office ? almost a de facto diplomatic post ? before it was closed in early 2009 in protest of Israeli attacks on Gaza. And Doha has been atop the Arab media pecking order as headquarters of the pan-Arab network Al-Jazeera, which was founded with Qatari government money in 1996 and is now expanding its English-speaking empire into the United States.
But it was the Arab Spring that opened the way for Qatar to stake out an even bigger role in regional affairs, filling the vacuum for regional powerhouse Egypt as that country was mired in turmoil after the revolution that ousted longtime leader Hosni Mubarak.
Qatar was among the few Arab states offering active military assistance to NATO-led attacks against Moammar Gadhafi's regime in Libya and, at the same time, was a key arms-and-money pipeline for Libyan rebels. In Egypt, Mubarak's fall offered Qatar's rapid-reaction outreach a head start over other Gulf states because of its longstanding ties with the now-governing Muslim Brotherhood.
Egyptian President Mohammed Morsi, who attended the Doha summit, has turned to Qatar to help prop up the country's stumbling economy.
"We expect that financial pledges will be respected," Morsi said in a message to Qatar and other Arab countries that have promised money for Egypt.
Almost nothing happens in the Syrian opposition without a voice from Qatar, which has played matchmaker for a broader political coalition against Syrian President Bashar Assad and leads appeals to provide rebel fighters more heavy weapons in attempts to turn the tide in the 2-year-old civil war. On Tuesday, Qatar led the official transfer of Syria's Arab League seat from the Assad government to the opposition Syrian National Coalition.
The New York Times reported Monday that the CIA has helped Turkey and Arab governments, including Qatar and Saudi Arabia, to sharply increase military aid to Syria's opposition in recent months with secret airlifts or arms and equipment. The Associated Press also reported, citing American officials and others, that the U.S. is training secular Syrian fighters in Jordan in a bid to stem the influence of Islamist radicals in the splintered Syrian opposition.
To view Qatar's rise as purely a triumph of extreme wealth gives an incomplete picture, analysts say. True, Qatar's pockets are deep. The most recent budget surplus swelled to $26 billion and Qatar has one of the world's most well-heeled sovereign wealth funds whose acquisitions include stakes in luxury brands such as Tiffany and the Valentino fashion house as well as David Beckham's new club, Paris Saint-Germain.
But Qatar represents a shift in Arab clout toward a new style: A country squarely in the Western-leaning camp, but far more willing to embark on policies and plans that could ruffle the U.S.
"Qatar believes it doesn't have to wait for others to try to shape the direction and conversation in the region," said Theodore Karasik, a security and political affairs analyst at the Dubai-based Institute for Near East and Gulf Military Analysis. "That kind of confidence opens up all kinds of new political equations."
A clear example was a centerpiece of the Arab League summit welcoming address by Qatar's ruler, Sheik Hamad bin Khalifa Al Thani, who pledged $250 million toward a proposed $1 billion fund to defend the Arab identity and history of Jerusalem against an expanding Israeli presence in traditional Arab districts.
"The Palestinian, Arab and Muslim rights in Jerusalem are not negotiable, and Israel must realize this," the emir said after telling other Arab states that it is their responsibility to kick in another $750 million.
Such Qatar-led initiatives are likely to deepen its influence among Palestinians and, indirectly, appear to further challenge Washington as the main outside policy-shaper in Israel-Palestinian disputes. Last year, Qatar's emir traveled to the Gaza Strip with promises for funds and assistance that also sought to undercut Iran as the principal backer for Hamas.
Hamas on Tuesday welcomed the emir's invitation to meet in Cairo with the rival Palestinian Authority for another round of reconciliation talks, which began last year in Qatar.
"Qatar has money to spend and the political will to use it as an extension of its foreign policy," according to Karasik, the analyst. "That's a powerful combination."
The Qatar government guest book is a case in point.
Qatar has offered debt-battered Italy and Greece separate 1 billion euro ($1.29 billion) funds for small businesses and traditional workshops if the countries match the amount. In the past few months, the prime ministers of Italy and Greece have come calling in Doha with words of thanks.
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Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza. The research is published online ahead of print in the Journal of Virology.
The strength of the new vaccine is that it uses attenuated, rather than "killed" virus. (Killed viruses are broken apart with chemicals or heat, and they are used because they are safer than attenuated viruses.) Killed virus vaccines against avian influenza are injected into the bloodstream, whereas this vaccine is given via nasal spray, thus mimicking the natural infection process, stimulating a stronger immune response.
The danger of current attenuated virus vaccines is that they might exchange dangerous genetic material with garden variety influenza viruses of the sort that strike annually, potentially rendering a lethal but very hard to transmit influenza virus, such as H5, easily transmissible among humans. To mitigate those dangers, the study authors, led by Daniel Perez of the University of Maryland, came up with an ingenious design. Influenza viruses carry their genetic material in eight "segments," explains coauthor and University of Maryland colleague Troy Sutton. When viruses reassort, they exchange segments. But each segment is unique, all eight are needed, and the viruses are unfit if they contain more than eight segments.
The vaccine is based on an attenuated version of the H9 virus, with an H5 gene added into one of the H9 virus' segments, to confer immunity to the H5 virus. Segment 8, which is composed of the so-called NS1 and NS2 genes, was split apart, and the NS2 gene was moved into segment 2, adjacent to the polymerase gene, which copies the virus' genetic material during replication. Placing NS2 next to the polymerase gene slowed its function, interfering with the virus' replication. That makes the vaccine safer.
The next step was to engineer the H5 gene into the vaccine. It was inserted into segment 8, where the NS2 gene had been.
Another aspect of the new vaccine's design makes it safer still, by rendering successful reassortment less likely. Both NS1 and NS2 are needed for viral replication. Since the two genes are now separated into different segments, any reassortment will have to include both segments, instead of just segment 8, in order for a reassortant virus to be viable. This greatly reduced the probability of successful reassortment.
The World Health Organization (WHO) recognizes avian influenza subtypes H5, H7, and H9 as potential pandemic viruses, because they all have in rare instances infected humans, and because they circulate in wild birds. Single reassortants could be sufficient to breach the species barrier, and since they do not circulate among us, we lack any immunity. Moreover, H5 is unusually lethal, having killed roughly half of those few it is confirmed to have infected.
###
American Society for Microbiology: http://www.asm.org
Thanks to American Society for Microbiology for this article.
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Mike Murphy is a web producer at the Mercury News, and also writes for Good Morning Silicon Valley and 60-Second Business Break.
Spotify is reportedly gearing up to challenge Netflix as a streaming-video provider.
According to a report by Business Insider?s Nicholas Carlson, the Sweden-based streaming music giant is seeking partners to help fund original ? and exclusive ? video content.
Entering the streaming video field already dominated by Netflix, Amazon and Hulu appears to be a daunting task at first glance, but it may be a profitable option for Spotify. According to the report, the high cost of licensing rights for streaming music makes Spotify?s profit margins razor thin, and the music labels can dictate their terms ? much like the problems Netflix has faced with streaming video. So instead of competing with rival services for studio-produced movies and TV shows, Spotify would create a new revenue stream by producing original content.
It?s a strategy that seems to be working for Los Gatos-based Netflix. After years of costly negotiations with studios and competing with cable channels for streaming rights, Netflix last year launched an effort to develop its own original content, and with it add more subscribers. Its first venture into original content, the David Fincher-Kevin Spacey drama ?House of Cards,? has proven to be a hit, and Netflix is betting on repeating that success with a new season of the cult-favorite sitcom ?Arrested Development? later this year.
Spotify is not the only one taking notice. YouTube, the home to billions of free online videos, is also considering adding subscription channels to create new revenue streams, according to a recent report by the Wall Street Journal. While still in the planning stages, subscription channels could be a boon for video makers with ?passionate but very narrow audience segments,? Lucas Watson, head of YouTube?s global sales, told the Journal.
Launched in the U.S. in 2011, Spotify already has more than 6 million subscribers and is launching an aggressive effort to land more with? its first major advertising campaign, according to a report by The Verge. By first solidifying its place as a leader in streaming music, the company could be in good position to branch out into new video ventures as home entertainment moves from the living room to the smartphone.
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Mike Murphy (197 Posts)Mike Murphy is a web producer at the Mercury News, and also writes for Good Morning Silicon Valley and 60-Second Business Break.
Source: http://www.siliconbeat.com/2013/03/25/spotify-may-be-taking-a-cue-from-netflix/
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Microsoft has reached an important milestone ? the Windows Store now touts more than 50,000 apps available for Windows 8 and Windows 8 RT.
The achievement was reached yesterday, according to the MetroStore Scanner, which at the time of writing counts 50,341 apps.
In the month of March alone, the statistic reads for around 279 daily apps on average pushed to the Store, making it one of the most successful months in the history of the store. The most active month yet has been last November though, when around 468 newborn apps were submitted to the Windows Store every day.
Last week Microsoft launched a new program for developers offering them $100 per every submitted app in the Windows 8 and Windows Phone 8 stores. Developers can snag a total of $2000, as the $100 are given for as much as 10 apps per OS. Furthermore, Microsoft is luring app creators with higher revenue split (80%/20%), a whole 10% more than what Apple and Google offer.
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The second weekend of the NCAA Basketball tournament takes place this week with the Sweet 16 and Elite 8, but hoops fans will also want to keep an eye on the streaking Miami Heat. Meanwhile, some sci fi / fantasy favorites are highlights thanks to their seasonal return or departure this week, but we'd also give new series like BBC America's Orphan Black a chance in between sessions of Bioshock: Infinite. Look below for the highlights this week, followed after the break by our weekly listing of what to look out for in TV, Blu-ray and videogames.
Doctor Who
Doctor Who is back, now featuring actress Jenna-Louise Coleman as companion Clara Oswald for the next half season. There's a preview trailer embedded after the break, and the BBC has a rundown of the first four episodes right here.
(March 30th, BBC America, 8PM)
The Walking Dead
This season of everyone's favorite zombie series is finally ready to wrap up with what we expect will be an epic showdown between the prison residents and Woodbury. Last season's finale certainly met our expectations in terms of action, we'll see if it can repeat or even top that effort this time around.
(March 31st, AMC, 9PM)
Game of Thrones
Winter is... still coming. Game of Thrones is back for season three and there is an appropriate amount of backstabbing, intrigue, violence and dragons to go around. By now we know what to expect from the lands of Westeros, if you need to be filled in check after the break for a recap of the last two seasons.
(March 31st, HBO, 9PM)
Filed under: Home Entertainment, HD
Source: http://www.engadget.com/2013/03/25/must-see-hdtv-march-25th-31st/
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Mar. 20, 2013 ? After outgrowing teenage infatuations with the girl next door, adult males seem to be biologically designed to avoid amorous attractions to the wife next door, according to a University of Missouri study that found adult males' testosterone levels dropped when they were interacting with the marital partner of a close friend. Understanding the biological mechanisms that keep men from constantly competing for each others' wives may shed light on how people manage to cooperate on the levels of neighborhoods, cities and even globally.
"Although men have many chances to pursue a friend's mate, propositions for adultery are relatively rare on a per opportunity basis," said Mark Flinn, professor of anthropology in the College of Arts and Science. "Men's testosterone levels generally increase when they are interacting with a potential sexual partner or an enemy's mate. However, our findings suggest that men's minds have evolved to foster a situation where the stable pair bonds of friends are respected."
Flinn says that these findings might help solve global problems.
"Ultimately, our findings about testosterone levels illuminate how people have evolved to form alliances," said Flinn. "Using that biological understanding of human nature, we can look for ways to solve global problems. The same physiological mechanisms that allow villages of families to coexist and cooperate can also allow groups like NATO and the U.N. to coordinate efforts to solve common problems. The more we view the Earth as a single community of people, the greater our ability to solve mutual threats, such as climate change."
Evolutionarily, men who were constantly betraying their friends' trust and endangering the stability of families may have caused a survival disadvantage for their entire communities, according to Flinn. A community of men who didn't trust each other would be brittle and vulnerable to attack and conquest. The costs of an untrustworthy reputation would have outweighed the benefits of having extra offspring with a friend's conjugal companion.
For example, a cautionary tale of the dangers of adultery can be found in the myth of Camelot. Sir Lancelot betrayed King Arthur by seducing Guinevere. Soon after, the fellowship of the Knights of the Round Table disintegrated and the kingdom fell. The alliance of powerful males could not hold once trust had been lost.
The study "Hormonal Mechanisms for Regulation of Aggression in Human Coalitions" was published in the journal Human Nature. Co-authors were Davide Ponzi of MU's Division of Biological Sciences in the College of Arts and Science and Michael Muehlenbein of Indiana University.
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KABUL, Afghanistan (AP) ? An Afghan official says a member of the country's government-backed militia has shot and killed five of his colleagues.
Badhis provincial government spokesman Mirwais Mirzakwal told The Associated Press on Friday that the shooting happened Thursday morning in a remote part of Qadis district.
The spokesman says investigators have been sent to the area where the shooting occurred but that he has limited information because the region is difficult to call over the telephone.
The attacker was a member of the Afghan Local Police, a program in which the government in Kabul and international allies train and fund villagers to mount defense forces against insurgents.
It was the latest in a string of insider attacks by members of the Afghan security forces against colleagues or international advisers.
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By Jon Blistein, Rolling Stone
Taking cross-branding to new highs, Bone Thugs-N-Harmony member Stanley "Flesh-N-Bone" Howse has partnered with a medical marijuana facility in Otisville, Mich., to create a new strain for patients in the area, Michigan Live reports.
Daniel Boczarski / Redferns file
Rapper Flesh-N-Bone performs on stage in Chicago in 2010.
"We worked closely together to figure out what we wanted out of the medication," said Anthony Butler, owner of the Green Oasis dispensary. The partnership will also allow Butler to further cultivate and distribute the strain and its seeds.
Bone Thugs-n-Harmony Call Reunion a 'Kick-Start to a Beautiful Situation'
"It's almost unreal," Butler added. "It's definitely an honor."
Dubbing the strain "Phifty Caliber Kush," Butler said it has a distinct floral taste and works as an effective pain reliever: "It's the best of the best," he said.
The budding relationship between Howse and Butler -- which may be the first of its kind -- came about after the owner of a company that specializes in marijuana-themed clothes (which Butler used to work for) put the two in contact following a discussion about who might like to get involved in the medical marijuana industry.
Michael "Tony B." Bernardi, executive of business affairs for Flesh-N-Bone Global, said that Howse hopes the new strain can provide relief for qualified patients and he's proud to be a part of a "paradigm shift in the culture" of medicinal marijuana. The Green Oasis may also start selling merchandise and it's possible Howse might visit the dispensary in the future.
While medicinal marijuana is legal in Michigan, the state's Supreme Court recently issued a ruling that allowed the state to shut down a dispensary for violating public health code. Michigan Attonrey General Bill Schuette said that the decision would further let the state close other facilities on the grounds they are a public nuisance.
In response to that interpretation, Butler has started charging only enough to reimburse the cost of growing the plant and sells only to patients he serves as a registered caregiver, leading to calls from bill collectors and keeping him from serving other patients in need. "I've seen my medicine help cancer patients, people with asthma," Butler said.
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More than three quarters of new, emerging or re-emerging human diseases are caused by pathogens from animals, according to the World Health Organization.
But a widely accepted theory of risk reduction for these pathogens ? one of the most important ideas in disease ecology ? is likely wrong, according to a new study co-authored by Stanford Woods Institute for the Environment Senior Fellow James Holland Jones and former Woods-affiliated ecologist Dan Salkeld.
The dilution effect theorizes that disease risk for humans decreases as the variety of species in an area increases. For example, it postulates that a tick has a higher chance of infecting a human with Lyme disease if the tick has previously had few animal host options beyond white-footed mice, which are carriers of Lyme disease-causing bacteria.
If many other animal hosts had been available to the tick, the tick's likelihood of being infected and spreading that infection to a human host would go down, according to the theory.
If true, the dilution effect would mean that conservation and public health agendas could be united in a common purpose: to protect biodiversity and guard against disease risk. "However, its importance to the field or the beauty of the idea do not guarantee that it is actually scientifically correct," said Jones, an associate professor of Anthropology.
In the first study to formally assess the dilution effect, Jones, Salkeld and California Department of Public Health researcher Kerry Padgett tested the hypothesis through a meta-analysis of studies that evaluate links between host biodiversity and disease risk for disease agents that infect humans.
The analysis, published in the journal Ecology Letters, allowed the researchers to pool estimates from studies and test for any bias against publishing studies with "negative results" that contradict the dilution effect.
The analysis found "very weak support, at best" for the dilution effect. Instead, the researchers found that the links between biodiversity and disease prevalence are variable and dependent on the disease system, local ecology and probably human social context.
The role of individual host species and their interactions with other hosts, vectors and pathogens are more influential in determining local disease risk, the analysis found.
"Lyme disease biology in the Northeast is obviously going to differ in its ecology from Lyme disease in California," Salkeld said. "In the Northeast, they have longer winters and abundant tick hosts. In California, we have milder weather and lots of Western fence lizards (a favored tick host) that harbor ticks but do not transmit the Lyme disease bacterium."
So, these lizards should be considered unique in any study of disease risk within their habitat. Or, as Salked put it, "All animals are equal, but some animals are more equal than others."
Broadly advocating for the preservation of biodiversity and natural ecosystems to reduce disease risk is "an oversimplification of disease ecology and epidemiology," the study's authors write, adding that more effective control of "zoonotic diseases" (those transmitted from animals to humans) may require more detailed understanding of how pathogens are transmitted.
Specifically, Jones, Salkeld and Padgett recommend that researchers focus more on how disease risk relates to species characteristics and ecological mechanisms. They also urge scientists to report data on both prevalence and density of infection in host animals, and to better establish specific causal links between measures of disease risk (such as infection rates in host animals) and rates of infection in local human populations.
For their meta-analysis, the researchers were able to find only 13 published studies and three unpublished data sets examining relationships between biodiversity and animal-to-human disease risk. This kind of investigation is "still in its infancy," the authors note. "Given the limited data available, conclusions regarding the biodiversity-disease relationship should be regarded with caution."
Still, Jones said, "I am very confident in saying that real progress in this field will come from understanding ecological mechanisms. We need to turn to elucidating these rather than wasting time arguing that simple species richness will always save the day for zoonotic disease risk."
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In an attempt to offer a compromise for UK viewers who may want to watch the occasional sporting event but don't want a full pay-TV package, Sky Sports is available in pay-as-you-go form on its Now TV service. Access won't come cheap however, priced at £9.99 for 24 hours of access to Sky's six sports channels. That does however open up streams for all of the sports it airs, like F1, soccer, cricket and more, on TV-connected devices like the Xbox 360 and its mobile apps. Check below the break for the details in the press
Filed under: Home Entertainment, HD
Source: Sky
Source: http://www.engadget.com/2013/03/19/sky-sports-comes-to-now-tv-9-99-for-24-hours/
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TAMPA, Fla. (AP) ? The trustee overseeing Casey Anthony's bankruptcy case has filed a motion to sell the rights to her story so she can pay her debts.
In a motion filed Friday in federal court in Tampa, trustee Stephen Meininger asked Judge K. Rodney May for permission to sell the "exclusive worldwide rights" of Anthony's life story.
Anthony, who is now 26, was acquitted of murder in the death her 2-year-old daughter, Caylee.
Anthony has never told her side of the story, despite intense media scrutiny of the case.
During a meeting with creditors in her bankruptcy case in Tampa on March 4, Anthony said she was unemployed and hasn't received any money to tell her story. She said that she is living with friends and that those friends ? and strangers who send her gift cards and cash ? help her survive.
But Meininger, through his attorney, said he thinks that her story has value and should be auctioned off to the highest bidder.
One man, Meininger wrote, has already offered to pay $10,000 for Anthony's life story so he can prevent her from publishing or profiting from it in the future.
Meininger points out that the man's offer is not contingent on Anthony's cooperation or participation. Anthony's life story ? including details about her childhood and the disappearance and death of Caylee ? is referred to as "the Property" in the motion.
"Due to the intense public interest in Debtor and the Property, the Trustee believes that there will be interest from others in purchasing the Property," the motion reads.
An auction, with bidding, is the "best way to maximize the value for the Estate and its creditors."
A call to David Schrader, Anthony's bankruptcy attorney, was not immediately returned.
Anthony filed for bankruptcy in Florida in late January, claiming about $1,000 in assets and $792,000 in liabilities. Court papers list Anthony as unemployed, with no recent income.
Her listed debts include $500,000 for attorney fees and costs for Jose Baez, her criminal defense lawyer during the trial; $145,660 for the Orange County Sheriff's office for investigative fees and costs; $68,540 for the Internal Revenue Service for taxes, interest and penalties; and $61,505 for the Florida Department of Law Enforcement for court costs.
The filling also states that she is a defendant in several lawsuits.
Source: http://news.yahoo.com/trustee-wants-sell-casey-anthonys-life-story-191757682.html
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Protesters hold up their hands as they protest outside the parliament in capital Nicosia, Cyprus, Monday, March 18, 2013. A vote on a bailout package for Cyprus that includes an immediate tax on all savings accounts has been postponed until Tuesday evening. Yiannakis Omirou, the speaker of Parliament, said the delay was needed to give the government time to amend the deal reached over the weekend that prompted an outcry from those who thought their money was safe. In order to get euro 10 billion ($13 billion) in bailout loans from international creditors, Cyprus agreed to take a percentage of all deposits ? including ordinary citizens' savings ? an unprecedented step in Europe's 3 ?-year debt crisis. (AP Photo/Petros Karadjias)
Protesters hold up their hands as they protest outside the parliament in capital Nicosia, Cyprus, Monday, March 18, 2013. A vote on a bailout package for Cyprus that includes an immediate tax on all savings accounts has been postponed until Tuesday evening. Yiannakis Omirou, the speaker of Parliament, said the delay was needed to give the government time to amend the deal reached over the weekend that prompted an outcry from those who thought their money was safe. In order to get euro 10 billion ($13 billion) in bailout loans from international creditors, Cyprus agreed to take a percentage of all deposits ? including ordinary citizens' savings ? an unprecedented step in Europe's 3 ?-year debt crisis. (AP Photo/Petros Karadjias)
Cypriot President Nicos Anastasiades, left, and President of the Parliament Yiannakis Omirou walk toward the parliament following a meeting in capital Nicosia, Cyprus, Monday, March 18, 2013. Cyprus' president is briefing lawmakers ahead of a crucial parliamentary vote on a controversial levy on bank deposits that the cash-strapped country's creditors have demanded in exchange for a euro10 billion (US$13 billion) rescue package.(AP Photo/Petros Karadjias)
A woman holds a banner during a protest outside of the parliament in Nicosia, Cyprus, Monday, March 18, 2013. A vote on a bailout package for Cyprus that includes an immediate tax on all savings accounts has been postponed until Tuesday evening. Yiannakis Omirou, the speaker of Parliament, said the delay was needed to give the government time to amend the deal reached over the weekend that prompted an outcry from those who thought their money was safe. In order to get euro 10 billion ($13 billion) in bailout loans from international creditors, Cyprus agreed to take a percentage of all deposits ? including ordinary citizens' savings ? an unprecedented step in Europe's 3 ?-year debt crisis. (AP Photo/Petros Karadjias)
Children run past a banner held by protestors outside of the Cyprus parliament during a crucial meeting in the capital, Nicosia, Monday, March 18, 2013. Cyprus' president is briefing lawmakers ahead of a crucial parliamentary vote on a controversial levy on bank deposits that the cash-strapped country's creditors have demanded in exchange for a euro10 billion (US$13 billion) rescue package. (AP Photo/Petros Karadjias)
Protesters who wrote "NO" on their hands protesting outside of the parliament in capital Nicosia, Cyprus, Monday, March 18, 2013. A vote on a bailout package for Cyprus that includes an immediate tax on all savings accounts has been postponed until Tuesday evening. Yiannakis Omirou, the speaker of Parliament, said the delay was needed to give the government time to amend the deal reached over the weekend that prompted an outcry from those who thought their money was safe. In order to get euro10 billion ($13 billion) in bailout loans from international creditors, Cyprus agreed to take a percentage of all deposits ? including ordinary citizens' savings ? an unprecedented step in Europe's 3 ?-year debt crisis. (AP Photo/Petros Karadjias)
NICOSIA, Cyprus (AP) ? A plan to seize up to 10 percent of savings accounts in Cyprus to help pay for a ?15.8 billion ($20.4 billion) financial bailout was met with fury Monday, and the government shut down banks until later this week while lawmakers wrangled over how to keep the island nation from bankruptcy.
Though the euro and stock prices of European banks fell, global financial markets largely remained calm, and there was little sense that bank account holders elsewhere across the continent faced similar risk.
Political leaders in Cyprus scrambled to devise a new plan that would not be so burdensome for people with less than ?100,000 ($129,290) in the bank.
The authorities delayed a parliamentary vote on the seizure of ?5.8 billion ($7.5 billion)and ordered banks to remain shut until Thursday while they try to modify the deal, which must be approved by other eurozone governments. Once a deal is in place, they will be ready to lend Cyprus ?10 billion ($13 billion) in rescue loans.
A rejection of the package could see the country go bankrupt and possibly drop out of the euro currency ? an outcome that would be even more damaging to financial markets' confidence.
Even while playing down the chance of fresh market turmoil, experts warned that the surprise move broke an important taboo against making depositors pay for Europe's bailouts. As a result, it may have longer-term consequences for confidence in Europe's banking system ? and its ability to end its financial crisis.
"It's a precedent for all European countries. Their money in every bank is not safe," said lawyer Simos Angelides at an angry protest outside parliament in Cyprus' capital, Nicosia, where people chanted, "Thieves, thieves!"
Eurozone finance ministers held a telephone conference Monday night, and concluded that small depositors should not be hit as hard as others. They said the Cypriot authorities will stagger the deposit seizures more, but they remained firm in demanding that the overall sum of money raised by the seizures remain the same.
In the short term, there was little sign of a new explosion in the European financial crisis. Stock markets dropped in early hours but stabilized by the close. The Dow Jones industrial average fell 62.05 points, or 0.4 percent, to 14,452.06 Monday. The euro fell 0.6 percent ? a bad day, but hardly a token of impending doom. Government bond prices for Italy and Spain were roughly unchanged, suggesting that investors do not expect the market trouble to spread beyond Cyprus for now.
In part, that may be due to the fact that Cyprus' case is by many measures an exception.
The decision to hit deposits up to ?100,000 ($129,290) ? the deposit insurance limit in Cyprus ? with a 6.75 percent tax and those above that with a 9.9 percent tax was dictated partly by the unusual qualities of the country's financial system.
Cyprus, with only 0.2 percent of the eurozone economy, has a bloated banking system seven times the size of the island's economy. Losses on Greek government bonds had crippled Cypriot banks and required government money to bail them out. Meanwhile, a large proportion of deposits ? 37 percent ? come from people outside Cyprus and the European Union, much of it from Russia.
European leaders wanted to limit the size of the rescue loans ? which are backed by European taxpayers ? to ?10 billion ($13 billion). Leaders were also reluctant to bail out Russian depositors whose funds may be the result of tax evasion, crime or money laundering.
Dario Perkins, an analyst at Lombard Street Research, noted that "the German government couldn't be seen bailing out Russian mafiosi just before an election."
He said the bailout also showed that European leaders were willing to decisively confront Cyprus' problem ? rather than postponing the day of reckoning with a partial solution. "On one level, you could argue this deal is good news," he wrote in a note to investors.
Officials say by tapping the depositors, they are reducing the total amount of debt taken on by the government, keeping it to a high but manageable 100 percent of GDP by 2020. That will mean less-painful austerity cutbacks than those that were imposed on Greece as a condition of its loans. Partly as a result, Greece is in the sixth year of recession.
Markets have been more resistant to new shocks since the European Central Bank's offer to purchase the bonds of indebted countries, lowering their borrowing costs. No bonds have been bought, but the offer's mere existence has calmed markets and left the eurozone far more resilient than it was a year ago. Last month's indecisive election in heavily indebted Italy, for instance, ruffled the market for only a day or two. Such fears were shortly dismissed by ECB President Mario Draghi as only "the angst of the week."
European authorities, meanwhile, have ways to defuse bank runs, should they occur. If depositors start withdrawing money, the ECB and national central banks can replace the funds with cheap credit through their emergency lending programs ? so long as the banks have securities to put up as collateral.
But down the road, the Cyprus precedent, even if quickly reversed, could come back to haunt eurozone policy makers by making depositors less sure about the safety of their money in case of trouble. It could also complicate creation of an EU-wide system of bank deposit insurance, part of long-term efforts to create a more robust financial system and prevent future crises.
Technically, the national deposit insurance scheme remains intact. The money is being taken as a one-time tax ? little comfort to those who thought their money was safe. If another eurozone country runs into a banking crisis, a run on the banks there will be more likely.
"The damage is done," said Louise Cooper, who heads financial research firm CooperCity in London. "Europeans now know that their savings could be used to bail out banks."
The deal adds uncertainty for depositors and investors because it underlines to ordinary people that there is no EU-wide deposit guarantee. Insuring deposits is a national responsibility ? and can only be done when the government has the money.
"Basically, Cyprus has not honored, at least as of Saturday morning, an obligation that is enshrined in EU legislation," said Nicholas Veron, a visiting fellow at the Peterson Institute for International Economics in Washington. "It clearly has consequences because I think there is a very clear message to depositors in Europe.
"It will not affect their behavior immediately, but it might affect their behavior in a future crisis," he said.
__
McHugh reported from Frankfurt, Germany. AP Business Writer Sarah Di Lorenzo in Paris contributed to this report.
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What works for me is
taking a multi vitamin and a vitamin c every morning
having a whey protein shake 2 times a day
working out (stay active, lift weights, it boosts your testosterone and will relieve stress)
AVOID PROCESSED FOODS (Greasy deep fried bullshit, McDonalds, wendys etc)
Seriously the preservatives they put in that shit is actually cancerous and really fucking bad.
Also, have a lot of fruits and vegtables (spinach >>>> salad fyi)
Back in HS I used to binge on unmentionables for ADD for days and I would feel like SHITTT after, but after I started this diet comedowns aren't nearly as bad and you always have more energy, feel happier etc.
IK this lifestyle sounds like shit,but seriously consider this diet though, after a couple weeks junk food just looks fucking nasty and healthy organics are really appealing (believe it or not, lol)
good luck at your job man! peace
__________________
Don't take life too seriously.
Source: http://forum.grasscity.com/real-life-stories/1193181-how-keep-energy-levels-high.html
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Gasoline prices and global temperatures are on the rise and so, once again, is pressure on Washington to take action on energy and climate change. The chance that the deadlocked Congress will strike a deal this year on a broad law to seriously reform the nation?s energy systems is slim to nil.
But a few cracks are emerging in that deadlock, with genuine bipartisan support gathering around a cluster of ideas linking energy priorities from both parties, such as offshore drilling and offshore wind power. The ideas aren?t comprehensive ? but even movement on a few small-bite energy bills would represent a big change from the politicized standoffs and sniping of recent years.?
Today, President Obama will highlight one of those ideas, and call on Congress to take action on it. For once, that might even happen.?
The venue and timing are appropriate: gasoline prices have soared 41 cents per gallon since the beginning of the year, and Obama will speak at the Energy Department?s Argonne National Laboratory, which researches electric cars and other alternative vehicle technology.
Against the backdrop of electric cars at a time when Americans are feeling the pain of higher gasoline costs, Obama will ask Congress to take action on an idea he first proposed last month in his State of the Union address: the creation of an energy trust fund that would research alternative-technology vehicles. The fund would get $2 billion over 10 years, not from taxpayer dollars, but from revenues generated by offshore oil and gas drilling. The idea is to channel money generated by drilling into a fund that researches technology that would ultimately lessen the nation?s dependence on oil ? and its global-warming emissions. It won?t be enough to end both problems, but it would be a small step in that direction.
In his State of the Union address, Obama said, ?Indeed, much of our newfound energy is drawn from lands and waters that we, the public, own together. So tonight, I propose we use some of our oil and gas revenues to fund an Energy Security Trust that will drive new research and technology to shift our cars and trucks off oil for good. If a nonpartisan coalition of CEOs and retired generals and admirals can get behind this idea, then so can we. Let?s take their advice and free our families and businesses from the painful spikes in gas prices we?ve put up with for far too long.?
The idea is the brainchild of the small Washington think tank Securing America?s Energy Future, which published a report in December recommending the creation of the trust fund ? although the SAFE proposal recommends funding the research through revenues generated by new, rather than existing offshore drilling. SAFE?s board of directors is headed by Fred Smith, the former Republican senator and former CEO of FedEx Corp., and retired Marine Corps General P.X. Kelley ? the pair mentioned in Obama?s speech.
On Dec. 3, the same day SAFE published the report, the group?s CEO, Robbie Diamond, met with both White House senior energy adviser Heather Zichal, and with the staff of Alaska's Sen. Lisa Murkowski, the top Republican on the Senate Energy Committee. Both the Democratic White House and the GOP senator liked the idea ?- and have since met to talk about moving it through Congress.
?Because of the bipartisan support for this program, we feel confident that our conversations with the Hill will be more fruitful,? Zichal told reporters in a conference call on Thursday. ?We feel really good about the partners we have,? Zichal said. The week before Obama?s State of the Union address, Murkowski unveiled an energy blueprint that also included a plan similar to SAFE?s energy trust fund ?- although key to the Republican plan was a reliance on revenue from new oil drilling, as the original SAFE plan had called for.
And Murkowski?s trust fund would fund all forms of energy research, not just advanced auto technology.
?The president hit on a good idea when he called for a trust fund to promote energy innovation,? said Robert Dillon, a spokesman for Murkowski. ?But unlike Sen. Murkowski?s proposal, he would not enable new energy production to pay for it. The president says he wants to divert a share of the royalties from offshore production that has already been factored into the budget, which could mean either deficit spending or less funding for the Land and Water Conservation Fund. The only other source would be new taxes. There?s a better way that not only funds investment in research, but also addresses our need for affordable and abundant energy. It?s Sen. Murkowski?s plan. We hope the president will embrace it.?
SAFE CEO Diamond ? who will be present at the president?s speech today, thinks those differences are surmountable.?
?The Republicans want to do this by expanding energy production ?- and Democrats should be in favor of it because you can have more money for research. There?s clearly room for negotiation,? he said.
Source: http://news.yahoo.com/obamas-energy-trust-fund-idea-gain-traction-congress-070925661--politics.html
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